GENOME-WIDE LINKAGE IN A HIGHLY CONSANGUINEOUS PEDIGREE REVEALS TWO NOVEL LOCI ON CHROMOSOME 7 FOR NON-SYNDROMIC FAMILIAL PREMATURE OVARIAN FAILURE.

Genome-wide linkage in a highly consanguineous pedigree reveals two novel loci on chromosome 7 for non-syndromic familial Premature Ovarian Failure.

BACKGROUND: The human condition known as Premature Ovarian Failure (POF) is characterized by loss of ovarian function before the age of 40.A majority of POF cases are sporadic, but 10-15% are familial, suggesting a genetic origin of the disease.Although several causal mutations have been identified, Phytoceramides the etiology of POF is still unkno

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A uncertainty visual analytics approach for bus travel time

Bus travel time is uncertain due to the dynamic change in the environment.Passenger analyzing bus travel time uncertainty has significant implications for understanding bus running errors and reducing travel risks.To quantify the uncertainty of the bus travel time prediction model, a visual analysis method about the bus travel time uncertainty is p

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Vasomotor reactions in the face and head of patients with migraine

Objective: To systematically review extracranial vasomotor reactions in patients with migraine, and to discuss potential overlaps with rosacea.Background: Autonomic manifestations are common in migraine and may reflect trigeminovascular system activation.Flushing during migraine attacks may indicate altered extracranial vasomotor reactivity which P

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